Synbiotic consortium
A microbiome approach to healthy insulin sensitivity, built from the genome up.*
GlycoTerra™ is a six-strain synbiotic designed for the place where your metabolism is quietly decided: the lining of your gut. One capsule a day, tested as a finished formula in people for six months.*
One capsule daily. Thirty capsules a jar. Take it for at least three to six months.
Discover the microbiome. Unlock your potential.
Insulin resistance is the defining metabolic condition of our time.
Most of us think about blood sugar at the plate. What we eat matters, and so does everything that happens to it afterward, in a part of the body that rarely gets a mention: the lining of your gut.
That lining is where trillions of microbes meet the rest of you. When the community is well fed and in balance, it helps keep the lining intact and turns fiber into the short-chain fatty acids your gut cells run on. When it drifts out of balance, the lining becomes the source of a steady, low-level inflammatory signal that travels outward and interferes with how your cells hear insulin.*
That community is not fixed. It shifts with diet, age, medication and environment, and it can be worked on. That is the whole idea behind GlycoTerra™.*
Designed to support healthy insulin function.*
Not just a lower number. Less pressure on the system.
GlycoTerra™ was evaluated as the finished formula in a randomized, double-blind, placebo-controlled human trial of 92 adults over six months, with the results published in a peer-reviewed journal. Most probiotics are assembled from studies of their individual strains. This one was tested the way it is sold.
Median fasting insulin decreased from 21.0 to 11.5 µIU/mL at 6 months (p=0.001).
Median HOMA-IR decreased from 4.9 to 3.2 at 6 months (p=0.020), with between-group superiority versus placebo (p=0.042).
Randomized, double-blind, placebo-controlled trial, n=92, six months. Median values, prediabetes participants in the GlycoTerra™ arm, baseline to month 6. Published in Microorganisms 2026;14:749. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Most probiotics are picked. This one was built.
GlycoTerra™ started with the biological functions we set out to support and worked backward, through host physiology, microbial ecology and comparative genomics, to the organisms best equipped to support them. Each of the six was chosen for what it does alongside the others, and the prebiotic substrates and metabiotic component were formulated with them from the start.
Biome E.N.G.I.N.E.™
Ecological Network-Guided Intelligent Next-generation Engineering. A closed-loop scientific operating system: every formulation makes the next one smarter.
Work backward from the function to the host pathways and microbial functions involved.
One target: the barrier.
GlycoTerra™ works with the ecosystem that is already in your gut, on two fronts at once: shifting the balance of the community, and supporting the lining that keeps gut contents where they belong.*
It gets through
Six organisms selected to survive the trip through the stomach and stay detectable for months.*
It shifts the balance
The six compete with less helpful, LPS-producing organisms for the same niches and the same food, and their fermentation output feeds the resident organisms that make butyrate.*
The barrier holds
Butyrate is the preferred fuel of the cells lining your colon, and a signal those cells use to maintain healthy tight junctions and a healthy mucus layer.*
The founder spent two decades tracing chronic disease back to one broken barrier.
Kiran Krishnan helped bring microbiome science into mainstream medicine, designing dozens of human clinical trials and educating more than 100,000 practitioners worldwide. One idea sits at the center of his work: the gut barrier.
When that barrier loses integrity, bacterial endotoxin (LPS) crosses into circulation and triggers chronic, low-grade inflammation, metabolic endotoxemia. Krishnan argues this is one of the most important upstream drivers of the diseases we associate with aging. GlycoTerra™ was engineered to act there, at the root, which is why the clinical signal that mattered most was the drop in circulating LPS.
"The microbiome behaves like a rainforest. No single species determines the health of the ecosystem. Health comes from balance, diversity, and countless organisms working together."
Kiran Krishnan
The formula.
Six functionally selected organisms, two prebiotic substrates and one metabiotic component, in a single vegetarian capsule.
What one capsule a day is built to support.
- ✓Helps maintain healthy blood sugar levels already within the normal range*
- ✓Supports healthy insulin sensitivity*
- ✓Supports healthy glucose metabolism*
- ✓Supports a healthy metabolic response to meals*
- ✓Supports a healthy gut barrier and a balanced gut microbiome*
- ✓Supports everyday digestive comfort and regularity*
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
One capsule. With a meal. Every day.
GlycoTerra™ is for adults who want to support healthy glucose metabolism, a healthy gut barrier and a balanced microbiome, and for anyone whose digestion suggests things are a little out of balance.* Ecosystems move at their own pace, so plan on giving it the same window the trial had.
Take 1 capsule daily with a meal or as directed by your healthcare practitioner. For best results, take for a minimum of 3 to 6 months and beyond.
If you are pregnant or nursing, taking any medications, or have a medical condition, consult your doctor before using this product. Keep out of reach of children. Do not use if safety seal is broken or missing.
The changes people noticed in daily life.
Mean change from baseline on a self-reported scale, over six months, against placebo.
These are patient-reported outcomes and were not adjusted for multiple comparisons.
Six months, taken daily, and well tolerated.
No one stopped taking GlycoTerra™ for safety reasons.
Participants took more than 94% of their capsules across six months.
Digestive symptoms were no more frequent than with placebo.
What people ask before they start.
Give it three months at least. The trial ran for six, and GlycoTerra™ works on a microbial community, which changes slowly.*
Because the two jobs are different. Competing with less helpful organisms for space and food is one problem; producing the fermentation output that your colon cells use is another. No single organism does both well, which is why the formulation is a consortium.*
Bacterial cell-wall fragments and metabolites that act without needing to be alive. GlycoTerra™ includes a Lactobacillus delbrueckii lysate alongside the live organisms.*
Two of them were still detectable at six months in the metagenomic subset of the trial, and were not detected at all in the placebo arm. Persistence after stopping was not assessed, so this shows survival through transit rather than permanent colonization.*
It is published in Microorganisms 2026;14:749. Licensed practitioners can request the full formulation and science brief, including the complete microbiome analysis.
Bring GlycoTerra™ into your practice.
The complete formulation and science brief, including the clinical endpoint data and the full microbiome dataset, is available to licensed practitioners. Wholesale accounts include practitioner pricing and direct support from our team.
Look deeper. Discover more.
Begin your GlycoTerra™ ritual: one capsule daily, engineered for your metabolic terrain.*
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Manufactured for Biome Learning Center, LLC, 800 Belle Terre Parkway, Suite 200 #341, Palm Coast, FL 32164.
Clinical data from García G, et al. Microorganisms 2026;14:749 (doi:10.3390/microorganisms14040749) and Díaz A, García G, Cano RJ, Ecological Engineering of the Human Gut Microbiome, Preprints 2026.
GlycoTerra™ and Biome E.N.G.I.N.E.™ are trademarks of Biome Learning Center, LLC.
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